WHITE BLOOD CELLS RATIOS IN PATIENTS WITH ACUTE CORONARY SYNDROMES IN ASSOCIATION WITH HYPERTENSION AND DIABETES MELLITUS

Introduction. Evidence now indicates that inflammation contributes considerably to the initiation and progression of atherosclerosis an active inflammatory processes may trigger plaque rupture enhance risk coronary thrombosis leading a clinical ischemic event. The purpose this study was evaluate white blood cells ratios in patients with ACS association arterial hypertension 2 type Diabetes Mellitus.
 Material Methods. In observational cohort trial we observed 184 ACS. All were randomized into four groups: 1st group - 42 without AH or DM; 2nd – 56 previous AH; 3rd 4th 44 DM. We studied leukocytes count their subpopulation ratios: neutrophils lymphocytes ratio (NLR), monocytes (NMR), lymphocytes+monocytes (N/LMR), (NMR).
 Results. mean significant higher ASC, compared control (p<0.001). elevated NMR NLR observed: 15.04±1.28 vs 11.09±0.43 (p<0.05), 3.34±0.20 2.60±0.06 respectively. No differences between WBC revealed and/or DM.
 Conclusion. is characterized raised which could be indicators poor prognosis.